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Mayo Clinic Research Fellow-Translational Omics Program in Rochester, Minnesota

City Rochester

State Minnesota

Telecommute No

Department Research

Why Mayo Clinic

The needs of patients drive research at Mayo Clinic. As doctors treat patients and see opportunities for advancing patient care, they work together with Mayo scientists and research teams to develop new and improved diagnostic tools, medications, devices, treatment protocols and more. Encouraging and including contributions from diverse individuals is critical to Mayo Clinic's future. By leveraging the strengths that each diverse individual and group brings to the table, Mayo Clinic gains the strategic advantages of accelerated innovation, better problem solving, enhanced productivity and job satisfaction, improved quality, and, most importantly, provides better ways to meet the needs of our patients.

Position description

We are currently seeking a motivated postdoctoral research fellow to join our team – Mayo Clinic’s Center for Individualized Medicine Translational Omics Program (TOP) .We are an innovative and driven team of investigators focused on the interpretation of -omic data for diagnostic and preventative clinical applications. Our primary research involves rare and/or undiagnosed monogenetic disease and preventative sequencing of health individuals. Mayo Clinic’s Center for Individualized Medicine was established to advance genomic sequencing into clinical practice and transform the way we care for patients. Our work involves close collaboration with medical geneticists and other providers starting with initial clinical genomic testing and then moving beyond the clinical results for patients still lacking a genetic diagnosis.

The TOP (also known as the TGP, Translational Genomics Program) team is charged with interrogating multiple -omic data in new ways with new algorithms, and using laboratory functional studies to clarify the effect of genetic variants and to prove causality of genes of uncertain clinical significance. We are embedded in an environment with a diverse group of motivated clinicians and investigators all striving to find answers for our patients. If you are passionate about genetics, capable of thinking outside the box, creative in your ability to solve the mysteries you are faced with, and able to interact in an energetic and driven collaborative team science environment, we invite you to apply for a research fellow position.


  • Analyze and interpret DNA, RNA, and other sequencing data to determine the genetic etiology of hereditary disease

  • Interpret genetic findings in the context of rare and undiagnosed disease, as well as, preventative (i.e. ‘healthy screen’) testing

  • Propose and facilitate research efforts to functionally characterize variants or genes of uncertain significance to determine pathogenicity

  • Communicate effectively with internal and external clinicians, researchers, and laboratorians

  • Establish and manage internal and external collaborations

  • Contribute to the development and improvement of analytical workflows for –omic data types and data integration

  • Applicants with experience in omic data analysis, including bioinformatics, biostatistics, and data science are also encourage to apply

  • Present findings and interpretation regularly to internal and external groups

  • Routinely write and publish scientific research, case reports, and methods papers

A Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants. Proof of English proficiency is required for J-1 Short-Term Scholars, Research Scholars, Professors, Specialists, and Student Interns sponsored by Mayo Clinic.

The following is required for completeness of application:

  • Current curriculum vitae with bibliography

  • Proof of doctoral degree (copy of diploma or final transcript with English translation, if applicable) or a letter from your university's Registrar office indicating you have fulfilled all doctoral program requirements and are eligible to graduate.

Please also be prepared that you may be asked to provide three letters of recommendation to the hiring PI prior to an interview.


Must have a Ph.D., M.D., or equivalent doctoral degree in a field deemed relevant by the program. Research Fellow is appropriate for individuals who have completed no more than one prior postdoctoral fellowship, at Mayo Clinic or elsewhere.

Benefits eligible Yes

Schedule Full Time

Site description

Mayo Clinic is located in the heart of downtown Rochester, Minnesota, a vibrant, friendly city that provides a highly livable environment for more than 34,000 Mayo staff and students. The city is consistently ranked among the best places to live in the United States because of its affordable cost of living, healthy lifestyle, excellent school systems and exceptionally high quality of life.

Category Postdoc & Temporary Research

Specialty Other

Job posting number 142698BR

Recruiter Katrina Giese

Equal opportunity

As an Affirmative Action and Equal Opportunity Employer Mayo Clinic is committed to creating an inclusive environment that values the diversity of its employees and does not discriminate against any employee or candidate. Women, minorities, veterans, people from the LGBTQ communities and people with disabilities are strongly encouraged to apply to join our teams. Reasonable accommodations to access job openings or to apply for a job are available.