Minnnesota Bioscience Jobs

Job Information

Mayo Clinic Senior Research Technologist in Rochester, Minnesota

City Rochester

State Minnesota

Telecommute No

Department Physiology & Biomedical Engineering

Why Mayo Clinic

The Research shield at Mayo Clinic is committed to creating a diverse environment and recognizes that diverse research teams make better decisions, are more equipped to solve complex problems and adapt to change, and produce better outcomes. That diversity is about opening up to unconventional ideas that create better outcomes, while recognizing colleagues' unique contributions. Become part of the legacy that embraces these differences and enables us to provide the best care to patients from all over the world.

Position description

A team of established Investigators within the Department of Physiology and Biomedical Engineering, with collaborators in the Division of Gastroenterology and Hepatology, is looking for highly motivated, well-trained individuals interested in expanding their horizons via bench and translational research in chronic gastrointestinal and hepatologic diseases using patient-derived cells. These efforts are part of an institutional Cells-to-Cures initiative that strives to establish multi-cellular platforms (commonly termed organoids) using cells from patients with such chronic diseases (obtained via biopsies and surgical samples) in an effort to accelerate our understanding of disease mechanisms, and to develop biomarkers and novel therapies.

The successful candidate will have the opportunity to work on various 3D organoid cultures derived from patient tissues and will be involved in the acquisition, processing, maintenance and down-stream applications of organoids. Applications will include biobanking, disease modeling, basic science studies, microfluidics, co-culture, and drug screening.

You will be expected to perform laboratory procedures in cell culture atmosphere for creation, culturing, maintenance and characterization of 3D organoids. You will work with the investigators to develop new protocols, test and evaluate a variety of approaches, and ensure successful creation of the organoid platforms. You will perform experiments and data analysis, document experimental observations and calculations, and summarize the findings. Troubleshooting of standard experiments is expected. You will present data at regular meetings, provide conclusions and future plans as directed by the investigative team.

The successful candidate should have demonstrated abilities to work collaboratively in a team with excellent verbal, written and presentation communication skills. The candidate is expected to be flexible and proficient with time management, with demonstrated ability to share and delegate tasks as necessary towards overall programmatic goals. Flexibility may also involve occasional evening and weekend availability to process tissues and samples based on timing of patient samples.



  • Requires bachelor's degree in biology, chemistry, or other relevant science with 4 years of research laboratory experience.

  • The successful candidate should have at least a Bachelor’s degree in the Biological Sciences or in the Engineering sciences that would provide the scientific and technical background for tissue processing, cell isolation and processing, cell culture, and assessment of cellular structure and function with approaches such as microscopy, immunostaining, gene/protein measurements, etc.

Additional qualifications

  • Master's degree in biology, chemistry, or other relevant science preferred.

  • Experience in working with 3D culture systems (such as organoids) is highly desirable, but relevant and extensive experience in 2D cell culture is required.

Exemption status Exempt

Compensation Detail

Education, experience and tenure may be considered along with internal equity when job offers are extended. The minimum salary every 2 weeks is approx $2,170.40, based on a full-time position.

Benefits eligible Yes

Schedule Full Time

Hours / Pay period 80

Schedule details 8am - 5pm, Monday - Friday

Weekend schedule Occasional weekends as needed.

Site description

Mayo Clinic is located in the heart of downtown Rochester, Minnesota, a vibrant, friendly city that provides a highly livable environment for more than 34,000 Mayo staff and students. The city is consistently ranked among the best places to live in the United States because of its affordable cost of living, healthy lifestyle, excellent school systems and exceptionally high quality of life.

Category Clinical Labs and Research

Career profile Research

Job posting number 148526BR

Recruiter Chadwick Musolf

Equal opportunity

As an Affirmative Action and Equal Opportunity Employer Mayo Clinic is committed to creating an inclusive environment that values the diversity of its employees and does not discriminate against any employee or candidate. Women, minorities, veterans, people from the LGBTQ communities and people with disabilities are strongly encouraged to apply to join our teams. Reasonable accommodations to access job openings or to apply for a job are available.